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FACTSHEET: The leading causes of death in Africa in 2012

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Africa Check has published an updated factsheet on the leading causes of death in Africa following the release of new data. Find it here.

By World Health Organisation (WHO) figures, the Ebola epidemic in West Africa claimed 8,037 lives between the start of the outbreak in 2014 and the end of that year. Though the virulence and rapid spread of the Ebola virus are major causes of concern, it is important to understand the mortality figures in the broader sub-Saharan African context.

In 2012 – the most recent complete WHO figures for the World Bank sub-Saharan African region – about 9.6-million people died in the region.

Many top killers preventable

Deaths in Africa in 2012 fell largely in the WHO Group 1 category (death through communicable diseases, and perinatal, maternal and nutritional causes): 5.9-million deaths amounting to 61.7% of all deaths in sub-Saharan Africa.

Group 2, death as a result of non-communicable diseases, accounted for 2.7-million deaths or 28.6% of all deaths. This category includes heart disease (293,000 deaths), various forms of cancer (426,000) and diabetes (175,000).

Group 3, deaths through injury, amounted to 939,000 deaths, or 9.8% of the total. Group 3 causes of death include unintentional injuries, such as road accidents (207,000), and intentional injuries, such as inter-personal violence (132,000) and collective violence (14,000).

Non-communicable and lifestyle diseases are the top killers in high-income countries, accounting for 67.8% of deaths in 2012. In contrast, many of the top killers in sub-Saharan Africa – lower respiratory tract infections, tuberculosis, diarrhoeal disease and malaria – are preventable and treatable, given adequate healthcare systems and resources.

According to the WHO’s figures, the five top killers in Africa in 2012 were:


  • lower respiratory tract infections,

  • diarrhoeal diseases,

  • malaria, and

  • strokes.

(Note: The 2012 figures below are drawn from the WHO’s Global Health Estimates summary tables for cause of death in 2000 and 2012. Given that the Ebola outbreak to the end of September 2014 had only affected countries in sub-Saharan Africa, data was drawn from the WHO’s summary table of the World Bank sub-Saharan Africa region. Data sources and methodology are available on the organisation’s Global Health Estimates webpage.)

1. AIDS-related deaths

A photo taken in November 2013 shows staff members of the Themba Lethu Clinic in Johannesburg, the largest antiretroviral treatment site in the country, posing behind candles commemorating World Aids Day on December 1. Photo: AFP/Alexander Joe

A photo taken in November 2013 shows staff members of the Themba Lethu Clinic in Johannesburg, the largest antiretroviral treatment site in the country, posing behind candles commemorating World Aids Day on December 1. Photo: AFP/Alexander Joe" />

Though the number of deaths in the region due to AIDS-related illnesses was estimated have dropped by 22% between 2001 and 2012, the number of deaths still amounted to a significant share of the world total: 70% of global deaths.

In 2012, more than 1.1-million people were thought to have died from AIDS-related illnesses in the region, an 11.5% share of the regional tally. In that year, roughly 25-million individuals in the region were living with HIV; about one in every 36 people.

The WHO’s Global Health Estimates are coded according to the International Classification of Diseases and Health Related Problems. This separates out tuberculosis deaths in HIV-positive and HIV-negative individuals. Tuberculosis deaths in HIV-positive individuals are classified as AIDS-related deaths, while in HIV-negative individuals such deaths are attributed to tuberculosis.

However, the figures do not paint an entirely accurate picture: particularly in countries where vital registration data – information on births, deaths, marriage and migration – are incomplete or inadequately recorded.

Deaths among HIV-positive individuals may be attributed to the contributing cause of death, such as tuberculosis, diarrhoeal diseases or lower respiratory tract infections, rather than the underlying cause (HIV/AIDS). Accuracy is further hampered as those issuing death certificates often do not know individuals’ HIV status, and the fact that many individuals simply do not get tested for the virus.

2. Lower respiratory tract infections

Lower respiratory tract infections are viral or bacterial infections that target the lower respiratory organs – the lungs and airways. Lower respiratory tract infections include pneumonia, influenza and bronchitis.

Pneumonia is a leading cause of death in children, accounting for 18% of global deaths in children under the age of five, most of them in sub-Saharan Africa and South Asia.

In 2012, lower respiratory tract infections were the second highest cause of death in sub-Saharan Africa, accounting for just over 1-million or 11.5% of deaths in the region.

Though tuberculosis is among the lower respiratory tract infections, it is categorised separately in the WHO cause of death statistics. It accounted for 2.4% of deaths (230,000 deaths) in sub-Saharan Africa in 2012. Pulmonary TB mostly attacks the lungs, but its extrapulmonary variant affects other parts of the body, including the brain, spine and kidneys and bones.

3. Diarrhoeal disease

Diarrhoeal disease causes most global deaths in children under the age of five. According to the WHO, there are an estimated 1.7-million cases of diarrhoeal disease in the world each year, with 780,000 children dying from diarrhoea.

In sub-Saharan Africa, about 644,000 people died from diarrhoea in 2012, accounting for 6.7% of deaths.

Diarrhoeal disease, generally caused by bacterial, viral or parasitic organisms, causes death through dehydration. Yet these deaths are preventable: according to the US Centers for Disease Control, 88% of diarrhoeal deaths are the result of unsafe water and inadequate sanitation and hygiene.

4. Malaria

A health worker sprays insecticide against mosquitos on April 28, 2014 in Koumassi, Ivory Coast. Photo: AFP/Sia Kambou

A health worker sprays insecticide against mosquitos on April 28, 2014 in Koumassi, Ivory Coast. Photo: AFP/Sia Kambou" />

In 2012 malaria, a mosquito-transmitted, parasitic disease, killed 618,000 people around the globe - 568,000 or 92% of them in sub-Saharan Africa.

The disease accounted for 5.9% of deaths in sub-Saharan Africa. Children are particularly vulnerable to malaria: in 2012, deaths in children under the age of five accounted for 41% of malaria deaths in sub-Saharan Africa.

According to ONE, an international advocacy organisation targeting poverty and preventable diseases, six African countries account for nearly half of global malaria cases: Nigeria, Democratic Republic of the Congo, Tanzania, Uganda, Mozambique and Cote d’Ivoire.

An increase in malaria interventions – the provision of insect-repellent mosquito nets and indoor spraying with insecticides, for example – has seen the number of deaths in sub-Saharan Africa fall from 812,000 in 2000 to 568,000 in 2012. Of 3.3-million lives saved through such interventions between 2000 and 2012, 3-million were of children under the age of five in Africa.

5. Stroke

Stroke is the second leading cause of death globally after coronary heart disease, accounting for 6.7-million deaths in 2012 - 427,000 or 6% of these were in sub-Saharan Africa. About 4.4% of total deaths in sub-Saharan Africa were the result of stroke.

During a stroke, blood carrying oxygen is cut off from the brain, potentially leading to brain damage, disability or death. Family history, age, gender and race can be determining factors for stroke. Additional risk factors include obesity, diet, diabetes, smoking, hypertension and cholesterol.

Other leading causes of death in sub-Saharan Africa

After the five top killers in sub-Saharan Africa in 2012, leading causes of death were preterm birth complications (393,000), birth asphyxiation and trauma (356,000), malnutrition (307,000), coronary heart disease (293,000) and meningitis (260,000). [Last update: 18/02/2015]

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