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Which African country has the highest burden of sickle cell disease in the world?

In much of Africa, over 1% of all newborns have sickle cell anemia. Nigeria alone is home to 25–35% of global sickle cell disease (SCD) births. Nigeria has been estimated to have at least 150,000 newborns born with SCD annually. Estimates are challenging because of the lack of federal newborn screening programmes; however, approximately 700,000 births occur per year and the prevalence of SCD in newborns was 3% in one regional newborn screening programme.

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